m-Chloroperbenzoic acid → HCID 20226928, compound

Participants

Reaction Steps

To a solution of 5-methyl-3-phenylpyridazine (2.0 g) in 40 mL of CHCl3 is added m-chloroperbenzoic acid (2.9 g, 80% pure). The solution is permitted to stand at room temperature until the reaction is complete. The precipitate which forms during the reaction period is removed by filtration, and the filtrate diluted with ether. The ether solution is then washed sequentially with 10% aqueous sodium sulfite, saturated sodium bicarbonate, and saturated brine. The washed liquid is dried over MgSO4 and then concentrated in vacuo to give 1.6 g (73%) of a pale yellow crystalline solid having a melting point of 112°-114° C.

Provenance & Evidence