Acetic Acid → HCID 13505189, compound

Participants

Reaction Steps

440 mg (1.31 mmol) of 6-(1-cyclohexen-4-yl)-4-methyl-β-carboline-3-carboxylic acid ethyl ester is heated under reflux for one hour in 20 ml of ethanol with 3.25 ml of 1N potassium hydroxide solution. After neutralizing with acetic acid and addition of 10 ml of water, the precipitated product is suctioned off, washed with water, and dried under vacuum over potassium hydroxide, thus obtaining 378 mg (94% of theory) of 6-(1-cyclohexen-4-yl)-4-methyl-β-carboline-3-carboxylic acid, mp 284°-285° C.

Provenance & Evidence