HCID 13505188, compound → HCID 13505206, compound

Participants

Reaction Steps

100 mg (0.3 mmol) of 6-(1-cyclohexen-4-yl)-4-methyl-β-carboline-3-carboxylic acid ethyl ester is hydrogenated in 20 ml of ethanol with 0.1 g of Raney nickel at room temperature for 2 hours under 10 bar. After separating from the catalyst, the product is evaporated and reprecipitated from a small amount of ethanol/hexane, thus obtaining 55 mg (54.7% of theory) of 6-cyclohexyl-4-methyl-3-β-carboline carboxylic acid ethyl ester, mp 191°-193° C.

Provenance & Evidence