Chloroform → 4,5-Dihydro-4,4-dimethyl-2-[4-(phenylmethoxy)phenyl]oxazole

HRID 173183Notes

Reaction equation

HRID 173183 reaction equation
[CH2:5]([c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1)[O:12][c:13]1[cH:14][cH:15][c:16]([C:17](=[O:18])[NH:19][C:20]([CH2:21][OH:22])([CH3:23])[CH3:24])[cH:25][cH:26]1.[CH:27]([Cl:28])([Cl:29])[Cl:30].[S:1]([Cl:2])([Cl:3])=[O:4]>>[CH2:5]([c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1)[O:12][c:13]1[cH:14][cH:15][c:16]([C:17]2=[N:19][C:20]([CH3:23])([CH3:24])[CH2:21][O:22]2)[cH:25][cH:26]1

Participants

4

Reactant 3

HCID 6212ChloroformHCID 24386Thionyl ChlorideHCID 141804474-(benzyloxy)-N-(2-hydroxy-1,1-dimethylethyl)benzamide

Product 1

HCID 149891694,5-Dihydro-4,4-dimethyl-2-[4-(phenylmethoxy)phenyl]oxazole

Sources & evidence

ORD record
ord-08b960f4a16140e19f7beba911963a37
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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