Benzenemethanamine, N-butyl- → N-Benzyl-N-butyl-N'-(2,4-dimethylphenyl)urea

HRID 1731832Notes

Reaction equation

HRID 1731832 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[N:9]=[C:10]=[O:11].[CH2:12]([NH:19][CH2:20][CH2:21][CH2:22][CH3:23])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>CCCCCC>[CH2:12]([N:19]([CH2:20][CH2:21][CH2:22][CH3:23])[C:10]([NH:9][C:3]1[CH:4]=[CH:5][C:6]([CH3:8])=[CH:7][C:2]=1[CH3:1])=[O:11])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 75467Benzenemethanamine, N-butyl-HCID 52075851-isocyanato-2,4-dimethylbenzene

Product 1

HCID 13732974N-Benzyl-N-butyl-N'-(2,4-dimethylphenyl)urea

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent2×

Procedure

A solution of 4.89 g of 2,4-dimethylphenylisocyanate in 100 ml of hexane is added to a solution of 4.41 g of N-benzyl-n-butylamine in 150 ml of hexane, and the solution is stirred at room temperature for 2 hours and then evaporated. The residual solid is recrystallized from pentane to yield 1-benzyl-1-(n-butyl)-3-(2,4-dimethylphenyl)urea, m.p. 70°-71° C.

Workup

  1. customevaporated
  2. customThe residual solid is recrystallized from pentane

Sources & evidence

ORD record
ord-d5f2bc07b4e44f7fa7a44d8cf79b7070
Source dataset
uspto-grants-1986_11
Patent number
US04623662

Reaction notes

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