HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron tribromide → N-Benzyl-N-butyl-N'-(3-chloro-2-hydroxyphenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | N-Benzyl-N-butyl-N'-(3-chloro-2-methoxyphenyl)urea | HCID 13732989 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-Benzyl-N-butyl-N'-(3-chloro-2-hydroxyphenyl)urea | HCID 13732993 | — |
Reaction Steps
A solution of 1.73 g of 1-benzyl-1-(n-butyl)-3-(2-methoxy-3-chlorophenyl)urea and 1.0 ml of boron tribromide in 40 ml of methylene chloride was stirred at ambient temperature for 3 days and diluted with water. The organic layer was separated, dried, and evaporated. The residue was crystallized from hexane to yield 1-benzyl-1-(n-butyl)-3-(2-hydroxy-3-chlorophenyl)urea, m.p. 59°-62° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04623662 |
| Source dataset | uspto-grants-1986_11 |
| ORD ID | ord-1b63257a9342406db6538da39da4c0cd |
| Source note | uspto-grants-1986_11 |