6-Aminohexanoic Acid → HCID 20184400, compound

HRID 1731876Notes

Reaction equation

HRID 1731876 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]([OH:9])=[O:8].[OH-].[Na+].[CH3:12][S:13](Cl)(=[O:15])=[O:14]>>[CH3:12][S:13]([CH:6]([CH2:5][CH2:4][CH2:3][CH2:2][NH2:1])[C:7]([OH:9])=[O:8])(=[O:15])=[O:14]

Participants

4

Reactant 3

HCID 5646-Aminohexanoic AcidHCID 14798Sodium HydroxideHCID 31297Methanesulfonyl chloride

Product 1

HCID 20184400HCID 20184400, compound

Procedure

Analogously to Example 20a, 65.6 g of ε-aminocaproic acid are reacted with 40 ml of methanesulfonyl chloride in the presence of 2N NaOH and the mixture is worked up. The DCA salt is prepared, and 42.3 g of melting point 134° are obtained.

Workup

  1. customThe DCA salt is prepared
  2. custom42.3 g of melting point 134° are obtained

Sources & evidence

ORD record
ord-c0812d5edd4543aa8b93b298fcec1e2a
Source dataset
uspto-grants-1986_11
Patent number
US04623715

Reaction notes

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