2-chloro-N,N-dimethylacetamide → 2-[2-fluoro-5-(7-trifluoromethyl[1,8]naphthyridin-4-yl)phenoxy]-N,N-dimethylacetamide
Reaction equation
[Cl:23][CH2:24][C:25](=[O:26])[N:27]([CH3:28])[CH3:29].[F:1][c:2]1[c:3]([OH:22])[cH:4][c:5](-[c:8]2[cH:9][cH:10][n:11][c:12]3[n:13][c:14]([C:18]([F:19])([F:20])[F:21])[cH:15][cH:16][c:17]23)[cH:6][cH:7]1>>[F:1][c:2]1[c:3]([O:22][CH2:24][C:25](=[O:26])[N:27]([CH3:28])[CH3:29])[cH:4][c:5](-[c:8]2[cH:9][cH:10][n:11][c:12]3[n:13][c:14]([C:18]([F:19])([F:20])[F:21])[cH:15][cH:16][c:17]23)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-56a7715954ce4c599d4520fc134c79d3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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