HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 5-(Bromomethyl)-α-methyl-2-nitrobenzenemethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | HCID 11769120 | HCID 11769120 | — |
| Product | 5-(Bromomethyl)-α-methyl-2-nitrobenzenemethanol | HCID 20226515 | — |
Reaction Steps
Compound 2 is synthesized in two steps from 1-(5-methyl-2-nitrophenyl) ethanone (1), which can be obtained as described by Doppler et al. (1979) Helv. Chem. Acta 62:291-303. Specifically, the ring methyl group is brominated using N-bromosuccinimide and then the benzylic ketone is reduced to an alcohol. Those procedures are described below.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04625014 |
| Source dataset | uspto-grants-1986_11 |
| ORD ID | ord-4b37a79c79a94d5bb2f61fd5cc7a7955 |
| Source note | uspto-grants-1986_11 |