Morpholine → 5-Azaindole

HRID 1732094Notes

Reaction equation

HRID 1732094 reaction equation
[NH:1]1[CH2:6][CH2:5]O[CH2:3][CH2:2]1.C[C:8]1[CH:9]=[N+:10]([O-])[CH:11]=CC=1[N+]([O-])=O>>[NH:1]1[C:6]2[C:5](=[CH:11][N:10]=[CH:9][CH:8]=2)[CH:3]=[CH:2]1

Participants

3

Reactant 2

HCID 8083MorpholineHCID 70633Pyridine, 3-methyl-4-nitro-, 1-oxide

Product 1

HCID 92205-Azaindole

Procedure

A process according to claim 15, wherein the adduct used is obtained by reacting 6 mols of morpholine with 3 mols of methyl or ethyl orthoformate per mol of 3-methyl-4-nitro-pyridine-1-oxide.

Workup

  1. customused is obtained

Sources & evidence

ORD record
ord-4e4cff1dc60743c2a7d37c3fe7c253a9
Source dataset
uspto-grants-1986_11
Patent number
US04625033

Reaction notes

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