1-Chloro-3-methyl-2-butene → HCID 53898318, compound

Participants

Reaction Conditions

Reaction Steps

In analogy to Example 1, 64 g (1.6 moles) of NaOH, 200 ml of toluene, and 15 g of tetrabutylammonium bromide were first introduced and heated to 75° C. To this mixture was added a mixture of 147.6 g (1.2 moles) of 2-propyl-2-pentenenitrile and 157 g (1.5 moles) of prenyl chloride within 2 hours in individual doses. The reaction mixture was further heated for 3 hours at 85° C. and subsequently processed according to Example 1. The yield in desired product was 103 g, corresponding to 44.9% of the theoretical.

Provenance & Evidence