4-Mercaptophenol → HCID 12894089, compound

HRID 1732192Notes

Reaction equation

HRID 1732192 reaction equation
BrC1C=C2C(=CC=1)N=C(S[C:13]1[CH:24]=[CH:23][C:16]([O:17][CH:18]([CH3:22])[C:19]([OH:21])=[O:20])=[CH:15][CH:14]=1)C=C2.Br[C:26]1[CH:35]=[CH:34][C:33]2[C:28](=[CH:29][CH:30]=[C:31]([Br:36])[CH:32]=2)[N:27]=1.SC1C=CC([OH:44])=CC=1>>[Br:36][C:31]1[CH:32]=[C:33]2[C:28](=[CH:29][CH:30]=1)[N:27]=[C:26]([O:44][C:13]1[CH:24]=[CH:23][C:16]([O:17][CH:18]([CH3:22])[C:19]([OH:21])=[O:20])=[CH:15][CH:14]=1)[CH:35]=[CH:34]2

Participants

4

Reactant 3

HCID 2401474-MercaptophenolHCID 203051542,6-DibromoquinolineHCID 20305164HCID 20305164, compound

Product 1

HCID 12894089HCID 12894089, compound

Procedure

Also, 2-(4-((6-bromo-2-quinolinyl)thio)phenoxy)propionic acid, m.p. 163°-169° C., was prepared by reacting 2,6-dibromoquinoline with 4-mercaptophenol as described hereinbefore. The corresponding 6-chloro substituted analog is among the preferred embodiments of the invention.

Sources & evidence

ORD record
ord-c38b941b008f44aeb205ab928dd63230
Source dataset
uspto-grants-1980_12
Patent number
US04236912

Reaction notes

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