HCID 22813299, compound → HCID 22813308, compound

HRID 1732215Notes

Reaction equation

[O:1]1[C@H:13]2[CH2:14][C@@H:15]([C:27]([O:29]C)=[O:28])[C@@H:16](/[CH:17]=[CH:18]/[C@@H:19]([OH:26])[CH:20]([F:25])[CH2:21][CH2:22][CH2:23][CH3:24])[C@H:12]2[CH2:11][C@@H:2]1[CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9]C)=[O:8].O1C2C[C@@H](C(O)=O)[C@@H](/C=C/[C@@H](O)C(F)CCCC)[C@H]2C[C@@H]1CCCCC(O)=O>>[O:1]1[C@H:13]2[CH2:14][C@@H:15]([C:27]([OH:29])=[O:28])[C@@H:16](/[CH:17]=[CH:18]/[C@@H:19]([OH:26])[CH:20]([F:25])[CH2:21][CH2:22][CH2:23][CH3:24])[C@H:12]2[CH2:11][C@@H:2]1[CH2:3][CH2:4][CH2:5][CH2:6][C:7]([OH:9])=[O:8]

Participants

Reactant 2

HCID 22813299HCID 22813299, compound

HCID 22813311HCID 22813311, compound

Product 1

HCID 22813308HCID 22813308, compound

Procedure

By the procedure of Example 3, [6S,8R,9S,11R,12S,15R]methyl 6,9-epoxy-11-carbomethoxy-16-fluoro-15-hydroxyprost-(13E)-enoate was converted to [6S,8R,11R,12S,15R]-6,9-epoxy-11-carboxy-16-fluoro-15-hydroxyprost-(13E)-enoic acid.

Sources & evidence

ORD record: ord-89f4ae8763e54425b59c995e91f60b78
Source dataset: uspto-grants-1980_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04237060

Reaction notes

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