化工社化工社 化学情報印刷レポート · 研究参考用
Ammonia → N-Benzylacrylamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | Benzylamine | HCID 7504 | — |
| 反応物 | 3-Hydroxypropanamide | HCID 4145140 | — |
| 触媒 | 2,6-Di-tert-butyl-4-methylphenol | HCID 31404 | — |
| 生成物 | N-Benzylacrylamide | HCID 139428 | 86.2% |
反応手順
59 g of β-hydroxypropionamide and 75 g of benzylamine were heated with 50 mg of 2,6-di-t-butyl-p-cresol for 7 hours in a temperature range of 120°-170° C. until the evolution of ammonia was complete. After adding 2.2 g of polyphosphoric acid distillation was carried out in an oil pump vacuum; the subsequent redistillation with the addition of 1 ml of sulphuric acid yielded 92 g of N-benzylacrylamide, Bp0.1 113° C., which crystallized in the receiver. Mp (crude product): 53° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04237067 |
| 出典データセット | uspto-grants-1980_12 |
| ORD ID | ord-344fc3d640a84449bbb4702a45accb0e |
| 出典メモ | uspto-grants-1980_12 |