m-Chloroperbenzoic acid → HCID 20305773, compound

Participants

Reaction Steps

11-Benzyloxy-1-bromo-6,10-dimethyl-2-oxo-undec-5-ene (15.6 g, 41 mM) in methylene chloride (250 ml) is treated with 85% m-chloroperbenzoic acid (8.35 g, 41 mM) in methylene chloride (200 ml) at 0° C. for 3 hours. The reaction mixture is washed with brine, saturated sodium sulfite, brine and then dried (Na2SO4). The solvent is removed in vacuo to give crude 11-benzyloxy-1-bromo-6,10-dimethyl-5,6-epoxy-undecan-2-one (17.5 g).

Provenance & Evidence