反应详情

2-Chlorobenzhydrazide (38.8 g) was dissolved in sodium hydroxide solution (9.18 g in 125 ml water). The solution was stirred and 4-methylbenzoyl chloride (35.2 g) added dropwise. The mixture was then stirred for 2 hours and the solid which precipitated was filtered off, washed with water and recrystallised from ethanol to give 30.0 g of the desired product, mp 204°-206° C.

1. stirringThe mixture was then stirred for 2 hours
2. customthe solid which precipitated
3. filtrationwas filtered off
4. washwashed with water
5. customrecrystallised from ethanol