Thionyl Chloride → HCID 20306079, compound

HRID 1732326Notes

Reaction equation

HRID 1732326 reaction equation
[Cl:1][C:2]1[C:13]([C:14](=[O:20])[C:15]2[S:19][CH:18]=[CH:17][CH:16]=2)=[CH:12][C:5]2[CH2:6][CH:7]([C:9](O)=[O:10])[O:8][C:4]=2[C:3]=1[Cl:21].S(Cl)([Cl:24])=O>C1C=CC=CC=1>[Cl:1][C:2]1[C:13]([C:14](=[O:20])[C:15]2[S:19][CH:18]=[CH:17][CH:16]=2)=[CH:12][C:5]2[CH2:6][CH:7]([C:9]([Cl:24])=[O:10])[O:8][C:4]=2[C:3]=1[Cl:21]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 12747881HCID 12747881, compound

Product 1

HCID 20306079HCID 20306079, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A benzene solution (25 ml.) containing 6,7-dichloro-2,3-dihydro-5-(2-thenoyl)benzofuran-2-carboxylic acid (3.4 g., 0.01 mole) and thionyl chloride (2 ml.) is refluxed for two hours. Evaporation of the benzene and excess thionyl chloride leaves the 6,7-dichloro-2,3-dihydro-5-(2-thenoyl)benzofuran-2-carbonyl chloride which is used in Step B without further purification.

Workup

  1. temperatureis refluxed for two hours
  2. customEvaporation of the benzene and excess thionyl chloride

Sources & evidence

ORD record
ord-da45d7117f4c42a58062d1873e3ac9be
Source dataset
uspto-grants-1980_12
Patent number
US04237144

Reaction notes

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