L 636499 → 3-Hydroxymethyl-8-nitro-dibenzo[b,f]thiepin-5,5-dioxide

HRID 1732358Notes

Reaction equation

HRID 1732358 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[S:13](=[O:15])(=[O:14])[C:12]3[CH:16]=[C:17]([C:20](O)=[O:21])[CH:18]=[CH:19][C:11]=3[CH:10]=[CH:9][C:8]=2[CH:23]=1)([O-:3])=[O:2].C1C2C=CC3C=CC=CC=3S(=O)(=O)C=2C=C(C(O)=O)C=1>>[OH:21][CH2:20][C:17]1[CH:18]=[CH:19][C:11]2[CH:10]=[CH:9][C:8]3[CH:23]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=[CH:6][C:7]=3[S:13](=[O:14])(=[O:15])[C:12]=2[CH:16]=1

Participants

3

Reactant 2

HCID 130562L 636499HCID 131518828-Nitrodibenzo[b,f]thiepin-3-carboxylic acid 5,5-dioxide

Product 1

HCID 203061673-Hydroxymethyl-8-nitro-dibenzo[b,f]thiepin-5,5-dioxide

Procedure

Repeat the process of Example 6, substituting an equivalent quantity of 8-nitrodibenzo[b,f]thiepin-3-carboxylic acid 5,5-dioxide for the dibenzo[b,f]thiepin-3-carboxylic acid 5,5-dioxide, to obtain the title product.

Sources & evidence

ORD record
ord-3c42b299c67447d796864be4bc00009b
Source dataset
uspto-grants-1980_12
Patent number
US04237160

Reaction notes

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