Isobutyraldehyde → HCID 70543745, compound

HRID 1732404Notes

Reaction equation

HRID 1732404 reaction equation
[NH2:1][CH2:2][C:3]1[CH:4]=[N:5][CH:6]=[CH:7][CH:8]=1.[CH:9](=O)[CH:10]([CH3:12])[CH3:11]>C1(C)C=CC=CC=1>[CH:9](=[C:4]1[C:3]([CH2:2][NH2:1])=[CH:8][CH:7]=[CH:6][NH:5]1)[CH:10]([CH3:12])[CH3:11]

Participants

4

Reactant 2

HCID 6561IsobutyraldehydeHCID 310183-Pyridinemethanamine

Product 1

HCID 70543745HCID 70543745, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

The procedure as in Example 1(a) is carried out except that 54.07 g (0.5 mol) of 3-aminomethylpyridine, 40 g (0.55 mol) of isobutyraldehyde and 75 ml of toluene are used. Distillation yields 80.1 g (0.495 mol) of isobutylidene-3-aminomethylpyridine; yield 98.8% of theory; b.p 106°-108° C./1.8×103Pa; nD20 =1.5103.

Workup

  1. distillationDistillation

Sources & evidence

ORD record
ord-ab3cd591ebe14b2fa1fb8d3a12de1ded
Source dataset
uspto-grants-1980_12
Patent number
US04237275

Reaction notes

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