Potassium tert-butoxide → HCID 13702609, compound

HRID 1732405Notes

Reaction equation

HRID 1732405 reaction equation
C(=[C:5]1[C:10]([CH2:11][NH2:12])=[CH:9][CH:8]=[CH:7][NH:6]1)C(C)C.[CH3:13][C:14]([O-])([CH3:16])[CH3:15].[K+]>C1(C)C=CC=CC=1>[N:6]1[CH:7]=[CH:8][CH:9]=[C:10]([CH:11]=[N:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH:5]=1

Participants

4

Reactant 2

HCID 23665647Potassium tert-butoxideHCID 70543745HCID 70543745, compound

Product 1

HCID 13702609HCID 13702609, compoundYield 2,062.8%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

The procedure is carried out as in Example 1(b) but with the use of 80.1 g (0.495 mol) of isobutylidene-3-aminomethylpyridine, 2.5 g (0.0223 mol) of potassium tert-butylate and 75 ml of toluene. After a reaction time of 1 hour at 30°-35° C., distillation yields 74.5 g (0.46 mol) of 3-pyridylmethylidene-isobutylamine; yield 93% of theory; b.p. 108° C./2×103Pa; nD20 =1.5198.

Workup

  1. distillationAfter a reaction time of 1 hour at 30°-35° C., distillation

Sources & evidence

ORD record
ord-a42033984bf84049af2cce817de11428
Source dataset
uspto-grants-1980_12
Patent number
US04237275

Reaction notes

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