Benzene → 3-Methylpyridine

HRID 1732424Notes

Reaction equation

HRID 1732424 reaction equation
[CH:1]1C=CC=CC=1.[N:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[CH3:1][C:9]1[CH:8]=[N:7][CH:12]=[CH:11][CH:10]=1.[N:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 241BenzeneHCID 1049Pyridine

Product 2

HCID 1049PyridineYield 98.4%HCID 79703-MethylpyridineYield 99.5%

Procedure

The condensate 13 led to the working up after addition of 1800 ml of benzene per hour separated into 2 phases. The aqueous phase was extracted with 1800 ml of benzene hourly. In the distillation of the benzene phases there resulted per hour 851 grams of pyridine and 862 grams of 3-methylpyridine corresponding to a yield of 98.4% of pyridine and 99.5% yield of 3-methylpyridine based on the content of reaction gases supplied.

Workup

  1. customseparated into 2 phases
  2. extractionThe aqueous phase was extracted with 1800 ml of benzene hourly
  3. distillationIn the distillation of the benzene phases

Sources & evidence

ORD record
ord-83e5a6089ee048f19222ff85cb071625
Source dataset
uspto-grants-1980_12
Patent number
US04237299

Reaction notes

Loading…