4'-Mercaptoacetanilide → HCID 28412385, compound

HRID 1732465Notes

Reaction equation

HRID 1732465 reaction equation
NC1C=CC(I)=CN=1.C(NC1C=CC(S)=CC=1)(=O)C.C[O-].[Na+].C(NC1C=CC([C:33]2([S:40][C:41]3[CH:46]=[CH:45][C:44]([NH:47][C:48](=[O:50])[CH3:49])=[CH:43][CH:42]=3)[CH:38]=[N:37][C:36]([NH2:39])=[CH:35][CH2:34]2)=CC=1)(=O)C>[Cu]>[C:48]([NH:47][C:44]1[CH:43]=[CH:42][C:41]([S:40][C:33]2[CH:34]=[CH:35][C:36]([NH2:39])=[N:37][CH:38]=2)=[CH:46][CH:45]=1)(=[O:50])[CH3:49]

Participants

6

Reactant 4

HCID 707774'-MercaptoacetanilideHCID 885792-Pyridinamine, 5-iodo-HCID 10942334Sodium MethoxideHCID 70595095HCID 70595095, compound

Product 1

HCID 28412385HCID 28412385, compound

Reagents, catalysts & solvents 1

HCID 23978CopperCatalyst

Procedure

5.5 G. (0.25 mole) of 2-amino-5-iodopyridine, 5.02 g. (0.030 mole) of 4-acetamidothiophenol and 1.6 g. of sodium methoxide 800 mg. of copper under the conditions as in Example 2 (A) one obtains 5.8 g. of 5(p-acetamidophenyl) 5-(p-acetamidophenylthio)2-amino pyridine m.p. 178°-179° C.

Sources & evidence

ORD record
ord-0e5e7b4c794a477f9a5dfcfd12aa5290
Source dataset
uspto-grants-1980_12
Patent number
US04237300

Reaction notes

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