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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 173251Generated: October 26, 2026

Dimethylformamide → 2-Chloro-5-[(2-methyl-4-thiazolyl)ethynyl]pyridine

https://huagongshe.com/reaction/173251

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantTetrabutylammoniumHCID 16028—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantFluoride IonHCID 28179—
Reactant2-Chloro-5-iodopyridineHCID 4397176—
Reactant2-Methyl-4-(2-(trimethylsilyl)ethynyl)-1,3-thiazoleHCID 10921442—
Product2-Chloro-5-[(2-methyl-4-thiazolyl)ethynyl]pyridineHCID 11564911—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-98ad7d88da41479b9a0254b252c0ff51
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)