HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanone, 2-amino-1-phenyl-, hydrochloride (1:1) → HCID 13646632, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanone, 2-amino-1-phenyl-, hydrochloride (1:1) | HCID 2723597 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 1-Nitro2-methylthio-2-methylsulphinylethylene | HCID 54487094 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 13646632 | HCID 13646632 | 60.4% |
Reaction Steps
α-Aminoacetophenone hydrochloride (6.87g, 0.040 mol) was mixed with 1-nitro-2-methylthio-2-methylsulphinylethylene (7.25g, 0.040 mol) in 300 ml dry methanol and warmed at 60°. Sodium methoxide (from 0.92g sodium, 0.080g atom) in methanol (25 ml) was added dropwise, with stirring, over about 10 minutes. After addition, the mixture was stirred at 60° for one hour, and then filtered to give 2-methylthio-3-nitro-4-phenylpyrrole 5.66g, m.p. 259-261° dec.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04238494 |
| Source dataset | uspto-grants-1980_12 |
| ORD ID | ord-3976658c52ed48ee9aec7fdaaa394157 |
| Source note | uspto-grants-1980_12 |