HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetoacetate → HCID 12688297, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Valeryl chloride | HCID 61186 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 12688297 | HCID 12688297 | — |
Reaction Steps
Sodium hydride (50% in oil, 39.6g) was added portionwise to a solution of ethyl acetoacetate (107.5g) in dry ether under nitrogen. Valeryl chloride (100g) was added dropwise over 21/2 hours to the stirred suspension, and then poured into distilled water (500 ml.), and the ether layer was separated off and dried. The ether was removed to give ethyl 2-valerylacetoacetate (142g) as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04238494 |
| Source dataset | uspto-grants-1980_12 |
| ORD ID | ord-212fc5c192b64c13bb763102bee57c75 |
| Source note | uspto-grants-1980_12 |