5-Chloro-2-methoxybenzoyl chloride → HCID 53938896, compound

HRID 1732660Notes

Reaction equation

HRID 1732660 reaction equation
Cl.[NH2:2][CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]([CH3:19])=[CH:12][CH2:13][C:14]([O:16]CC)=[O:15])=[CH:7][CH:6]=1.[Cl:20][C:21]1[CH:22]=[CH:23][C:24]([O:30][CH3:31])=[C:25]([CH:29]=1)[C:26](Cl)=[O:27]>>[Cl:20][C:21]1[CH:22]=[CH:23][C:24]([O:30][CH3:31])=[C:25]([CH:29]=1)[C:26]([NH:2][CH2:3][CH2:4][C:5]1[CH:6]=[CH:7][C:8]([C:11]([CH3:19])=[CH:12][CH2:13][C:14]([OH:16])=[O:15])=[CH:9][CH:10]=1)=[O:27]

Participants

3

Reactant 2

HCID 123841765-Chloro-2-methoxybenzoyl chlorideHCID 70592591HCID 70592591, compound

Product 1

HCID 53938896HCID 53938896, compound

Procedure

By the reaction of ethyl γ-[4-(2-aminoethyl)-phenyl]-but-2-ene-carboxylate hydrochloride with 5-chloro-2-methoxybenzoyl chloride, there is obtained γ-{4-[2-(5-chloro-2-methoxybenzamido)-ethyl]-phenyl}-but-2-ene-carboxylic acid; m.p. 180°-183° C., after reprecipitation.

Sources & evidence

ORD record
ord-a43fc22451f04f9897db34d02e0150fe
Source dataset
uspto-grants-1980_12
Patent number
US04238506

Reaction notes

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