4-Chlorobenzoyl chloride → HCID 20304427, compound

HRID 1732664Notes

Reaction equation

HRID 1732664 reaction equation
Cl.[NH2:2][CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([O:19]CC)=[O:18])=[CH:7][CH:6]=1.[Cl:22][C:23]1[CH:31]=[CH:30][C:26]([C:27](Cl)=[O:28])=[CH:25][CH:24]=1>>[Cl:22][C:23]1[CH:31]=[CH:30][C:26]([C:27]([NH:2][CH2:3][CH2:4][C:5]2[CH:6]=[CH:7][C:8]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:9][CH:10]=2)=[O:28])=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 85014-Chlorobenzoyl chlorideHCID 20304456HCID 20304456, compound

Product 1

HCID 20304427HCID 20304427, compound

Procedure

By the reaction of ethyl 6-[4-(2-aminoethyl)-phenyl]-hexane-carboxylate hydrochloride with 4-chlorobenzoyl chloride, there is obtained 6-{4-[2-(4-chlorobenzamido)-ethyl]-phenyl}-hexane-carboxylic acid; m.p. 140°-143° C., after recrystallization from ethanol/diethyl ether.

Sources & evidence

ORD record
ord-542c3b50cab241718cc3c362ed280647
Source dataset
uspto-grants-1980_12
Patent number
US04238506

Reaction notes

Loading…