4-Piperidone hydrochloride → HCID 20304766, compound

HRID 1732697Notes

Reaction equation

HRID 1732697 reaction equation
N[N:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH:6]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[O:5][CH2:4][CH2:3]1.[ClH:19].[NH:20]1[CH2:25][CH2:24][C:23](=O)[CH2:22][CH2:21]1>>[ClH:19].[C:13]1([CH:6]2[C:7]3[CH:12]=[CH:11][CH:10]=[C:9]4[C:22]5[CH2:21][NH:20][CH2:25][CH2:24][C:23]=5[N:2]([C:8]=34)[CH2:3][CH2:4][O:5]2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 30848514-Piperidone hydrochlorideHCID 20304772HCID 20304772, compound

Product 1

HCID 20304766HCID 20304766, compound

Procedure

1-Amino-1,2,3,5-tetrahydro-5-phenyl-4,1-benzoxazepine [Testa and Fontanella, Il Farmaco, 18, 815 (1963)] is reacted with 4-piperidone hydrochloride as described in Example 110 to yield the title compound, m.p. 297°-299°.

Sources & evidence

ORD record
ord-6cb5472f137f4899bd7cf4e133b8cb76
Source dataset
uspto-grants-1980_12
Patent number
US04238607

Reaction notes

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