Hydrogen Bromide → HCID 12660548, compound

Participants

Reaction Steps

A solution of 31.12 g (0.1 mol) of tris(N-carbomethoxyaminomethyl)phosphine oxide in 100 ml of constant-boiling (47-49%) hydrobromic acid was heated to reflux with constant stirring. Within a few minutes, solids started to separate. The mixture was heated at reflux for one hour, cooled, and filtered. The filter cake, rinsed with ethanol and air-dried, afforded 18.95 g (49.9% yield) of tris(aminomethyl)phosphine oxide trihydrobromide as a white, crystalline solid, dec. 233° C. with reddening. Another 2.60 g (6.8% yield) was recovered from the filtrate after heating at reflux an additional hour.

Provenance & Evidence