反应详情

A mixture of 7 g. (0.03 M) of 4-chloro-7-methylpyrido[3',2':4,5]thieno[3,2-d]-1,2,3-triazine, and 7 g. (0.09 M) of thiourea in 350 ml. ethanol was refluxed for 2 hours. It was then cooled and filtered. The crude product was dissolved in 5% NaOH, and treated with charcoal and filtered. Acidification with HOAC followed by filtration yielded yellow solid, m.p. 205°-208° C.

1. additionA mixture of 7 g
2. temperatureIt was then cooled
3. filtrationfiltered
4. dissolutionThe crude product was dissolved in 5% NaOH
5. additiontreated with charcoal
6. filtrationfiltered
7. filtrationAcidification with HOAC followed by filtration
8. customyielded yellow solid, m.p. 205°-208° C.