Sulfuryl chloride → HCID 12593651, compound

HRID 1732936Notes

Reaction equation

HRID 1732936 reaction equation
[CH3:1][N:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5](=[O:12])[C:4]2[CH2:13][S:14][CH2:15][C:3]1=2.S(Cl)(Cl)(=O)=O>C(Cl)Cl>[CH3:1][N:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[C:5](=[O:12])[C:4]2=[CH:13][S:14][CH:15]=[C:3]12

Participants

4

Reactant 2

HCID 24648Sulfuryl chlorideHCID 12593643HCID 12593643, compound

Product 1

HCID 12593651HCID 12593651, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2.17 Parts of 1,4-dihydro-4-methylthieno-[3,4-b]-quinolin-9(3H)-one are reacted with 0.88 part by volume of sulfuryl chloride in 25 parts by volume of methylene chloride at 0° C. for 0.5 hour. The end product is isolated from the reaction mixture by the method described in Example 5c. 1.50 parts (70% of theory) of 4-methyl-thieno-[3,4-b]-quinolin-9(4H)-one of the melting point 188°-190° C. are obtained.

Workup

  1. customThe end product is isolated from the reaction mixture by the method

Sources & evidence

ORD record
ord-d8aa83f2a3b145c8b5d93eb4bdeab52f
Source dataset
uspto-grants-1980_12
Patent number
US04239897

Reaction notes

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