Chlorine → HCID 20303519, compound

Participants

Reaction Steps

A cooled solution of 8 g (113 mmoles) of chlorine in 50 ml of chloroform is added dropwise at 0° C. to a solution of 19.8 g (103 mmoles) of 1-(3-chloro-p-tolyl)pyrazole in 100 ml of chloroform, and stirring is effected for a further 2 hours at from 3° to 8° C. The organic phase is washed with water and dilute sodium dithionite solution; drying is effected, followed by concentration to dryness to produce 21.2 g (91% of theory) of 4-chloro-1-(3-chloro-p-tolyl)pyrazole (m.p. 69° to 70° C.).

Provenance & Evidence