Morpholine → HCID 70595222, compound

HRID 1733050Notes

Reaction equation

HRID 1733050 reaction equation
Cl[CH2:2][CH2:3][C:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([OH:6])[CH3:5].[NH:19]1[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1>>[O:22]1[CH2:23][CH2:24][N:19]([CH2:2][CH2:3][C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)([OH:6])[CH3:5])[CH2:20][CH2:21]1

Participants

3

Reactant 2

HCID 8083MorpholineHCID 70595719HCID 70595719, compound

Product 1

HCID 70595222HCID 70595222, compound

Procedure

2.6 g of 1-chloro-3-p-biphenylyl-butan-3-ol are boiled with 30 ml of morpholine for 1.5 hours and the mixture is cooled and worked up in the customary manner to give 1-morpholino-3-p-biphenylyl-butan-3-ol, m.p. 116°-118°.

Workup

  1. temperaturethe mixture is cooled

Sources & evidence

ORD record
ord-82cd8dff25574442abe0cac1ce85aaa3
Source dataset
uspto-grants-1980_12
Patent number
US04239759

Reaction notes

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