Isopropylamine → HCID 70595162, compound

HRID 1733054Notes

Reaction equation

HRID 1733054 reaction equation
[C:1]1([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]([CH3:11])[CH2:8][CH2:9]O.[CH:18]([NH2:21])([CH3:20])[CH3:19]>[Ni]>[CH:18]([NH:21][CH2:9][CH2:8][CH:7]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:11])([CH3:20])[CH3:19]

Participants

4

Reactant 2

HCID 6363IsopropylamineHCID 70595301HCID 70595301, compound

Product 1

HCID 70595162HCID 70595162, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

2.26 g of 3-p-biphenylylbutan-1-ol are dissolved in 10 ml of isopropylamine and, after adding 0.5 g of Raney nickel, the solution is shaken for 15 hours at 160° in a tube. After cooling, filtering off the catalyst and evaporating, 1-isopropylamino-3-p-biphenylyl-butane is obtained.

Workup

  1. temperatureAfter cooling
  2. filtrationfiltering off the catalyst
  3. customevaporating

Sources & evidence

ORD record
ord-e21a5f3224f94094be00558d1623d46c
Source dataset
uspto-grants-1980_12
Patent number
US04239759

Reaction notes

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