Pyridine → HCID 20302164, compound

HRID 1733061Notes

Reaction equation

HRID 1733061 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([CH:14]([CH3:18])[CH2:15][CH2:16][NH2:17])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.N1C=CC=CC=1.[C:25](Cl)(=[O:27])[CH3:26]>O>[C:25]([NH:17][CH2:16][CH2:15][CH:14]([C:11]1[CH:12]=[CH:13][C:8]([C:5]2[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=2)=[CH:9][CH:10]=1)[CH3:18])(=[O:27])[CH3:26]

Participants

5

Reactant 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 20302066HCID 20302066, compound

Product 1

HCID 20302164HCID 20302164, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 2.6 g of of 3-(4'-chloro-4-biphenylyl)butylamine, 12 ml of pyridine and 1 ml of acetyl chloride is allowed to stand for 2 hours, decomposed with water and worked up in the customary manner to give 1-acetamido-3-(4'-chloro-4-biphenylyl)-butane, m.p. 118°-120°.

Sources & evidence

ORD record
ord-62b7e21df7f24070b7de98d226b41db2
Source dataset
uspto-grants-1980_12
Patent number
US04239759

Reaction notes

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