HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1733075Generated: October 27, 2026
Acetic Acid → 19-Methoxy-androst-4-ene-3beta,17beta-diol
https://huagongshe.com/reaction/1733075
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 19-Methoxyandrost-4-ene-3,17-dione | HCID 54153042 | — |
| Catalyst | Water | HCID 962 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 19-Methoxy-androst-4-ene-3beta,17beta-diol | HCID 57239969 | — |
Reaction Steps
19-Methoxyandrost-4-ene-3,17-dione is dissolved in methanol and the solution cooled to 0° C. Sodium borohydride is added over a period of fifteen minutes and stirring continued for an additional two hours. The solution is poured into water containing a few drops of acetic acid. The white precipitate which forms is collected by filtration, dried and crystallized from acetone to yield the desired 19-methoxy-androst-4-ene-3β,17β-diol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04239681 |
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| Source dataset | uspto-grants-1980_12 |
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| ORD ID | ord-06a80b17f2b043328d7706c6280c28de |
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| Source note | uspto-grants-1980_12 |
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