HCID 86734750, compound → HCID 70585938, compound

HRID 1733081Notes

Reaction equation

HRID 1733081 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].[OH:5][CH2:6][C@@:7]12[C@@H:24]3[C@H:15]([C@H:16]4[C@@:20]([CH2:22][CH2:23]3)([CH3:21])[C:19](=[O:25])[CH2:18][CH2:17]4)[CH2:14][C@H:13]([CH3:26])[C:12]1=[CH:11][C:10](=[O:27])[CH2:9][CH2:8]2.[C:28](O)(=[O:30])[CH3:29].[OH:32][CH2:33][C@@:34]12[C@@H]3[C@H]([C@H]4[C@@](CC3)(C)C(=O)CC4)CC[C:39]1=[CH:38][C:37](=O)[CH2:36][CH2:35]2>>[C:1]([O:4][CH2:26][C@@:13]12[C@@H:14]3[C@H:37]([C@H:36]4[C@@:23]([CH2:24][CH2:15]3)([CH3:22])[C@@H:33]([OH:32])[CH2:34][CH2:35]4)[CH2:38][CH2:39][C:12]1=[CH:11][C@@H:10]([OH:27])[CH2:9][C@H:8]2[CH3:7])(=[O:3])[CH3:2].[C:28]([O:5][CH2:6][C@@:7]12[C@@H:24]3[C@H:15]([C@H:16]4[C@@:20]([CH2:22][CH2:23]3)([CH3:21])[C@@H:19]([OH:25])[CH2:18][CH2:17]4)[CH2:14][C@H:13]([CH3:26])[C:12]1=[CH:11][C@@H:10]([OH:27])[CH2:9][CH2:8]2)(=[O:30])[CH3:29]

Participants

4

Reactant 2

HCID 86734750HCID 86734750, compoundHCID 86735680HCID 86735680, compound

Product 2

HCID 70585938HCID 70585938, compoundHCID 70585976HCID 70585976, compound

Procedure

Substituting 19-hydroxy-1β-methyl-4-androstene-3,17-dione acetate and 19-hydroxy-6α-methyl-4-androstene-3,17-dione acetate for 19-hydroxyandrost-4-ene-3,17-dione acetate in the above procedure results in the formation of 1β-methyl-4-androstene-3β,17β,19-triol 19-acetate and 6α-methyl-4-androstene-3β,17β,19-triol 19-acetate.

Sources & evidence

ORD record
ord-e536f204dfcd4f928889496d61d2220f
Source dataset
uspto-grants-1980_12
Patent number
US04239681

Reaction notes

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