HCID 20300276, compound → HCID 20300267, compound

HRID 1733128Notes

Reaction equation

HRID 1733128 reaction equation
[C:1]([NH:4][C:5]1[N:17]=[C:8]2[C:9]3[C:14]([CH2:15][CH2:16][N:7]2[N:6]=1)=[CH:13][CH:12]=[CH:11][CH:10]=3)(=O)[CH3:2].[H-].[Al+3].[Li+].[H-].[H-].[H-]>C(COC)OC>[CH2:1]([NH:4][C:5]1[N:17]=[C:8]2[C:9]3[C:14]([CH2:15][CH2:16][N:7]2[N:6]=1)=[CH:13][CH:12]=[CH:11][CH:10]=3)[CH3:2]

Participants

4

Reactant 2

HCID 20300276HCID 20300276, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 20300267HCID 20300267, compoundYield 53%

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

2-Acetamido-5,6-dihydro-s-triazolo[5,1-a]isoquinoline is reduced with lithium aluminum hydride at 0°-10° C. in dimethoxyethane. Yield 53%, m.p. 100°-101° C.

Sources & evidence

ORD record
ord-3476d036b2f347289bd804d552c3d83f
Source dataset
uspto-grants-1980_12
Patent number
USRE030456

Reaction notes

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