HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Chloro-N-(3-cyano-4,5-dimethyl-2-furanyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | 2-Amino-4,5-dimethyl-3-furancarbonitrile | HCID 290220 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-Chloro-N-(3-cyano-4,5-dimethyl-2-furanyl)acetamide | HCID 16227354 | 122.3% |
Reaction Steps
20.4 g (0.1 mole) of 2-amino-3-cyano-4,5-dimethylfurane and 17.5 g (0.155 mole) of chloroacetyl chloride were boiled in 200 ml of toluene until the evolution of hydrogen chloride had subsided. Thereafter, the solvent was evaporated off under reduced pressure and the residue was recrystallized from ethyl acetate. 26 g of 2-chloroacetylamino-3-cyano-4,5-dimethylfurane of melting point 114° C. were obtained in this manner.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04240820 |
| Source dataset | uspto-grants-1980_12 |
| ORD ID | ord-732f528106744e908873ac48e9d38c0e |
| Source note | uspto-grants-1980_12 |