Hydrochloric Acid → HCID 20300394, compound

Participants

Reaction Steps

A slurry of 1.5 grams of 4-chloro-1-cyclohexylbenzotriazole, 15 grams of sodium methoxide, 10 grams of cuprous iodide in 50 milliliters of 2,4,6-trimethyl pyridine (collidine) and 10 milliliters of methanol is heated at the reflux temperature for 26 hours. The reaction is cooled and poured into 150 milliliters of 10% hydrochloric acid. The product is extracted with ethyl ether and on evaporation of the solvent, 0.5 grams of an oil is obtained which solidified on standing. The crude product is recrystallized from ethyl ether, m.p. 118°-120° C. The analytical sample has a m.p. 133°-134° C.

Provenance & Evidence