2-Chloroethyl isocyanate → HCID 54565757, compound

HRID 1733207Notes

Reaction equation

HRID 1733207 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@H:7]([CH2:9][OH:10])[OH:8])[OH:6])[OH:4].[CH3:11][O:12][CH:13]([CH3:16])[CH2:14][NH2:15].[Cl:17][CH2:18][CH2:19][N:20]=[C:21]=[O:22]>>[Cl:17][CH2:18][CH2:19][NH:20][C:21]([N:15]([CH2:14][CH:13]([O:12][CH3:11])[CH3:16])[CH:9]1[O:10][CH2:2][C@H:3]([OH:4])[C@H:5]([OH:6])[C@H:7]1[OH:8])=[O:22]

Participants

4

Reactant 3

HCID 160352-Chloroethyl isocyanateHCID 5460291aldehydo-L-arabinoseHCID 126097192-Methoxypropan-1-amine

Product 1

HCID 54565757HCID 54565757, compoundYield 45.9%

Procedure

3.0 g of L-arabinose, 3.6 g of 2-methoxy-n-propyl-amine and 3.5 g of 2-chloroethyl isocyanate are treated in the same manner as described in Example 13-(1). 3.0 g of 1-(2-chloroethyl)-3-(2-methoxy-n-propyl)-3-(L-arabinopyranosyl)urea are thereby obtained as colorless caramel.

Sources & evidence

ORD record
ord-60e1c1c7cd424d38a566804fe576bc0b
Source dataset
uspto-grants-1980_12
Patent number
US04241053

Reaction notes

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