Nitrogen oxide (N2O4) → HCID 53921138, compound

HRID 1733210Notes

Reaction equation

HRID 1733210 reaction equation
[Cl:1][CH2:2][CH2:3][NH:4][C:5]([N:7]([CH:17]([CH3:21])[CH2:18][O:19][CH3:20])[CH:8]1[O:16][CH2:15][C@H:13]([OH:14])[C@H:11]([OH:12])[C@H:9]1[OH:10])=[O:6].[N+:22]([O-])([N+]([O-])=O)=[O:23]>>[Cl:1][CH2:2][CH2:3][N:4]([N:22]=[O:23])[C:5]([N:7]([CH:17]([CH3:21])[CH2:18][O:19][CH3:20])[CH:8]1[O:16][CH2:15][C@H:13]([OH:14])[C@H:11]([OH:12])[C@H:9]1[OH:10])=[O:6]

Participants

3

Reactant 2

HCID 25352Nitrogen oxide (N2O4)HCID 54569619HCID 54569619, compound

Product 1

HCID 53921138HCID 53921138, compoundYield 27.8%

Procedure

3.3 g of 1-(2-chloroethyl)-3-(1-methyl-2-methoxy-ethyl)-3-(L-arabinopyranosyl)urea and 5 g of nitrogen tetroxide gas are treated in the same manner as described in Example 10-(2). 1.0 g of 1-(2-chloroethyl)-1-nitroso-3-(1-methyl-2-methoxy-ethyl)-3-(L-arabinopyranosyl)urea are thereby obtained as yellow caramel.

Sources & evidence

ORD record
ord-b6a82033dd8f4980bb63099e217d62c0
Source dataset
uspto-grants-1980_12
Patent number
US04241053

Reaction notes

Loading…