Nitrogen oxide (N2O4) → HCID 54075939, compound

HRID 1733212Notes

Reaction equation

HRID 1733212 reaction equation
[Cl:1][CH2:2][CH2:3][NH:4][C:5]([N:7]([CH2:17][CH2:18][CH2:19][O:20][CH3:21])[CH:8]1[O:16][CH2:15][C@@H:13]([OH:14])[C@@H:11]([OH:12])[C@@H:9]1[OH:10])=[O:6].[N+:22]([O-])([N+]([O-])=O)=[O:23]>>[Cl:1][CH2:2][CH2:3][N:4]([N:22]=[O:23])[C:5]([N:7]([CH2:17][CH2:18][CH2:19][O:20][CH3:21])[CH:8]1[O:16][CH2:15][C@@H:13]([OH:14])[C@@H:11]([OH:12])[C@@H:9]1[OH:10])=[O:6]

Participants

3

Reactant 2

HCID 25352Nitrogen oxide (N2O4)HCID 54230429HCID 54230429, compound

Product 1

HCID 54075939HCID 54075939, compoundYield 55.7%

Procedure

3.3 g of 1-(2-chloroethyl)-3-(3-methoxy-n-propyl)-3-(D-arabinopyranosyl)urea and 5 g of nitrogen tetroxide gas are treated in the same manner as described in Example 10-(2). 2.0 g of 1-(2-chloroethyl)-1-nitroso-3-(3-methoxy-n-propyl)-3-(D-arabinopyranosyl)urea are thereby obtained as pale yellow powder.

Sources & evidence

ORD record
ord-b30241d17cd74bcc81a5fa29d39c1a1a
Source dataset
uspto-grants-1980_12
Patent number
US04241053

Reaction notes

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