4-Toluenesulfonyl chloride → HCID 15573074, compound

Participants

Reaction Steps

In 10 ml of dioxane were dissolved 24.2 mg of the product of Example 2, followed by addition of 19.0 mg of p-toluenesulfonyl chloride and 10 mg of sodium carbonate. The mixture was stirred at room temperature for 4 hours and the resultant crystals were recovered by filtration and recrystallized from methanol to yield 35 mg of the title compound as colorless needles, m.p. 230°-231° C. Yield 89.7%.

Provenance & Evidence