Nitrogen oxide (N2O4) → HCID 88774696, compound

HRID 1733237Notes

Reaction equation

HRID 1733237 reaction equation
[Cl:1][CH2:2][CH2:3][NH:4][C:5]([N:7]([CH2:19][CH2:20][CH2:21][N:22]1[CH2:27][CH2:26][O:25][CH2:24][CH2:23]1)[CH:8]1[O:16][C@H:15]([CH2:17][OH:18])[C@H:13]([OH:14])[C@H:11]([OH:12])[C@H:9]1[OH:10])=[O:6].[N+:28]([O-])([N+]([O-])=O)=[O:29]>>[Cl:1][CH2:2][CH2:3][N:4]([N:28]=[O:29])[C:5]([N:7]([CH2:19][CH2:20][CH2:21][N:22]1[CH2:27][CH2:26][O:25][CH2:24][CH2:23]1)[CH:8]1[O:16][C@H:15]([CH2:17][OH:18])[C@H:13]([OH:14])[C@H:11]([OH:12])[C@H:9]1[OH:10])=[O:6]

Participants

3

Reactant 2

HCID 25352Nitrogen oxide (N2O4)HCID 53937360HCID 53937360, compound

Product 1

HCID 88774696HCID 88774696, compoundYield 54.7%

Procedure

4.1 g of 1-(2-chloroethyl)-3-(3-morpholinopropyl)-3-(D-galactopyranosyl)urea and 5 g of nitrogen tetroxide gas are treated in the same manner as described in Example 23-(2). 2.4 g of 1-(2-chloroethyl)-1-nitroso-3-(3-morpholinopropyl)-3-(D-galactopyranosyl)urea are thereby obtained as yellow caramel.

Sources & evidence

ORD record
ord-66f804e4990c42d79def2b26c01b0f32
Source dataset
uspto-grants-1980_12
Patent number
US04241052

Reaction notes

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