2-Chloroethyl isocyanate → HCID 54546902, compound

HRID 1733240Notes

Reaction equation

HRID 1733240 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@H:7]([CH2:9][OH:10])[OH:8])[OH:6])[OH:4].[CH:11]1([CH2:14][NH2:15])[CH2:13][CH2:12]1.[Cl:16][CH2:17][CH2:18][N:19]=[C:20]=[O:21]>>[Cl:16][CH2:17][CH2:18][NH:19][C:20]([N:15]([CH2:14][CH:11]1[CH2:13][CH2:12]1)[CH:9]1[O:10][CH2:2][C@H:3]([OH:4])[C@H:5]([OH:6])[C@H:7]1[OH:8])=[O:21]

Participants

4

Reactant 3

HCID 160352-Chloroethyl isocyanateHCID 75646CyclopropanemethanamineHCID 5460291aldehydo-L-arabinose

Product 1

HCID 54546902HCID 54546902, compoundYield 38.9%

Procedure

3.0 g of L-arabinose, 2.2 g of cyclopropylmethylamine and 2.5 g of 2-chloroethyl isocyanate are treated in the same manner as described in Example 23-(1). 2.4 g of 1-(2-chloroethyl)-3-cyclopropylmethyl-3-(L-arabinopyranosyl) urea are thereby obtained as colorless caramel.

Sources & evidence

ORD record
ord-eabc4d3d17194d93aaeb2d372e53db19
Source dataset
uspto-grants-1980_12
Patent number
US04241052

Reaction notes

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