2-Chloroethyl isocyanate → HCID 54427625, compound

HRID 1733249Notes

Reaction equation

HRID 1733249 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@H:7]([CH2:9][OH:10])[OH:8])[OH:6])[OH:4].[S:11]1[CH:15]=[CH:14][CH:13]=[C:12]1[CH2:16][NH2:17].[Cl:18][CH2:19][CH2:20][N:21]=[C:22]=[O:23]>>[Cl:18][CH2:19][CH2:20][NH:21][C:22]([N:17]([CH2:16][C:12]1[S:11][CH:15]=[CH:14][CH:13]=1)[CH:9]1[O:10][CH2:2][C@H:3]([OH:4])[C@H:5]([OH:6])[C@H:7]1[OH:8])=[O:23]

Participants

4

Reactant 3

HCID 160352-Chloroethyl isocyanateHCID 34005(2-Thienylmethyl)amineHCID 5460291aldehydo-L-arabinose

Product 1

HCID 54427625HCID 54427625, compound

Procedure

3.0 g of L-arabinose, 2.7 g of (thiophen-2-yl-methyl)amine and 2.5 of 2-chloroethyl isocyanate are treated in the same manner as described in Example 31-(1). 4.1 g of 1-(2-chloroethyl)-3-(thiopen-2-yl-methyl)-3-(L-arabinopyranosyl)urea are thereby obtained as colorless powder.

Sources & evidence

ORD record
ord-0e5a202e1dac461686160ba5687ff526
Source dataset
uspto-grants-1980_12
Patent number
US04241052

Reaction notes

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