反应详情

404.5 g of 3-(p-tert.butyl-phenyl)-2-methyl-acrolein are dissolved in 2500 ml of methanol and treated portionwise with 38 g of sodium borohydride while cooling with ice. Subsequently, the mixture is stirred at room temperature for 2.5 hours, poured into 2500 ml of ice-cold 2-N hydrochloric acid and exhaustively extracted with hexane. The combined hexane extracts are washed neutral with water, dried over sodium sulphate and evaporated. Vacuum distillation yields pure 3-(p-tert.butyl-phenyl)-2-methyl-allyl alcohol of boiling point 119° C./0.005 Torr.

1. temperaturewhile cooling with ice
2. extractionexhaustively extracted with hexane
3. washThe combined hexane extracts are washed neutral with water
4. dry with materialdried over sodium sulphate
5. customevaporated
6. distillationVacuum distillation