Sodium Hydroxide → 1-(3-acetylthio-2-trifluoromethylpropanoyl)-L-proline sodium salt

HRID 1733342Notes

Reaction equation

HRID 1733342 reaction equation
[C:1]([S:4][CH2:5][CH:6]([C:17]([F:20])([F:19])[F:18])[C:7]([N:9]1[CH2:16][CH2:15][CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8])(=[O:3])[CH3:2].[OH-].[Na+:22]>O>[Na+:22].[C:1]([S:4][CH2:5][CH:6]([C:17]([F:18])([F:19])[F:20])[C:7]([N:9]1[CH2:16][CH2:15][CH2:14][C@H:10]1[C:11]([O-:13])=[O:12])=[O:8])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 541522191-(3-acetylthio-2-trifluoromethylpropanoyl)-L-proline

Product 1

HCID 887813571-(3-acetylthio-2-trifluoromethylpropanoyl)-L-proline sodium salt

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A suspension of 1-(3-acetylthio-2-trifluoromethylpropanoyl)-L-proline (1 g.) in water (10 ml.) is adjusted to pH 8 by addition of normal sodium hydroxide. The resulting solution is freeze dried to yield 1-(3-acetylthio-2-trifluoromethylpropanoyl)-L-proline sodium salt.

Workup

  1. customdried

Sources & evidence

ORD record
ord-2c5f622cbbb6480399ac055b1ad0f2fa
Source dataset
uspto-grants-1980_12
Patent number
US04241076

Reaction notes

Loading…