Allyl bromide → HCID 178460855, compound

Participants

Reaction Steps

To a suspension of 3-iminophenylmethyl-4-(3-carbomethoxythioureido)benzophenone (2.09 g.; 0.005 mole) in acetone (40 ml.) and water (6.0 ml.) is added an aqueous sodium hydroxide solution (50% aqueous; 0.4 g.). The suspension is stirred at room temperature for one hour and then allyl bromide (0.6 g.; 0.005 mole) is added and the solution is stirred at room temperature over the weekend. The precipitate which forms is collected by filtration and then dried to afford 1.3 g. of 3-iminophenylmethyl)-4-(3-carbomethoxy-S-allylisothioureido)benzophenone, m.p. 125°-127° C.

Provenance & Evidence